Endocrine Abstracts

Background: Diabetes-related ketoacidosis (DKA) is a common and potentially life threatening complication in people with diabetes. Despite national and international guidelines, interhospital guideline variation and mismanagement during admission are important contributory factors to increased DKA duration and length of stay.Aim: To establish a common DKA registry to identify gaps in management, assess outcomes and share best practises across centres.</p...

Background: There are several good practices to improve DKA management across hospitals. However, the lack of a unified system limits comparisons and learning from each other.Objectives: To establish a DKA registry to identify best practices across centres in the West Midlands.Methods: All people admitted with DKA at four hospitals in the West Midlands (named A, B, C, D for anonymity) from 1st January 2020 to 31st December 2020 wer...

Introduction: Diabetes-related ketoacidosis (DKA) is an acute endocrine emergency requiring immediate diagnosis and management. Common misconception is that DKA is associated with type 1 diabetes only. We explored the proportion of people with type 2 diabetes, and compared the management, complications and outcome of DKA between people with type 1 and type 2 diabetes.Methods: We conducted a retrospective study on people admitted with DKA across six hospi...

Background: Serious complications of diabetes-related ketoacidosis (DKA) and its management with fixed rate insulin infusion (FRIII) include hypoglycaemia, hyperkalaemia and hypokalaemia. Revised Joint British Diabetes Societies for Inpatient Care (JBDS) guidelines in July 2021 recommended a reduced rate FRIII of 0.05 units/kg/hour from 0.1 units/kg/hour once blood glucose levels fall to ≤14.0 mmol/l to alleviate the risk of these complications.Aim...

Background: Diabetic ketoacidosis (DKA) is the most common acute endocrine complication needing hospital admission. Morbidity and mortality resulting from DKA are largely preventable if we can identify and act on gaps in management in relation to current guidelines.Objectives: To establish a common DKA registry to identify gaps in management and share best practices across centres.Methods: All people admitted with DKA at four hospi...

Introduction: Joint British Diabetes Societies Inpatient (JBDS-IP) recommended reducing fixed-rate intravenous insulin infusion (FRIII) rate to 0.05units/kg/hr when blood glucose falls <14 mmol/l to avoid hypoglycaemia during diabetes-related ketoacidosis (DKA).Aim: We studied the impact of guideline change on complications and outcomes of DKA.Methods: We included all DKA episo...